Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox checked   Rule 13d-1(c)
Checkbox not checked   Rule 13d-1(d)






SCHEDULE 13G




Comment for Type of Reporting Person:  (1) The shares reported in the table above are held directly by Soleus Capital Master Fund, L.P. ("Master Fund"). Soleus Capital, LLC is the sole general partner of Master Fund, Soleus Capital Group, LLC is the sole managing member of Soleus Capital, LLC, Soleus Capital Management, L.P. ("SCM ") is the investment manager for Master Fund, and Soleus GP, LLC is the sole general partner of SCM. Guy Levy is the sole managing member of each of Soleus Capital Group, LLC and of Soleus GP, LLC. Each of Soleus Capital Group, LLC, Soleus Capital, LLC, SCM, Soleus GP, LLC and Mr. Levy disclaims beneficial ownership of these shares held by Master Fund other than for the purpose of determining their obligations under Section 13(d) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such shares for any other purpose. (2) The percentage set forth in row 11 is calculated based upon 20,163,250 shares of the common stock of Praxis Precision Medicines, Inc. (the "Issuer") outstanding as of February 26, 2025, as reported on the cover of the Issuer's Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the Securities and Exchange Commission on February 28, 2025 (the "Form 10-K").


SCHEDULE 13G




Comment for Type of Reporting Person:  (1) The shares reported in the table above are held directly by Master Fund. Soleus Capital, LLC is the sole general partner of Master Fund, Soleus Capital Group, LLC is the sole managing member of Soleus Capital, LLC, SCM is the investment manager for Master Fund, and Soleus GP, LLC is the sole general partner of SCM. Guy Levy is the sole managing member of each of Soleus Capital Group, LLC and of Soleus GP, LLC. Each of Soleus Capital Group, LLC, Soleus Capital, LLC, SCM, Soleus GP, LLC and Mr. Levy disclaims beneficial ownership of these shares held by Master Fund other than for the purpose of determining their obligations under Section 13(d) of the Exchange Act, and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such shares for any other purpose. (2) The percentage set forth in row 11 is calculated based upon 20,163,250 shares of common stock of the Issuer outstanding as of February 26, 2025, as set forth on the cover of the Form 10-K.


SCHEDULE 13G




Comment for Type of Reporting Person:  (1) The shares reported in the table above are held directly by Master Fund. Soleus Capital, LLC is the sole general partner of Master Fund, Soleus Capital Group, LLC is the sole managing member of Soleus Capital, LLC, SCM is the investment manager for Master Fund, and Soleus GP, LLC is the sole general partner of SCM. Guy Levy is the sole managing member of each of Soleus Capital Group, LLC and of Soleus GP, LLC. Each of Soleus Capital Group, LLC, Soleus Capital, LLC, SCM, Soleus GP, LLC and Mr. Levy disclaims beneficial ownership of these shares held by Master Fund other than for the purpose of determining their obligations under Section 13(d) of the Exchange Act, and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such shares for any other purpose. (2) The percentage set forth in row 11 is calculated based upon 20,163,250 shares of common stock of the Issuer outstanding as of February 26, 2025, as set forth on the cover of the Form 10-K.


SCHEDULE 13G




Comment for Type of Reporting Person:  (1) The shares reported in the table above are held directly by Master Fund. Soleus Capital, LLC is the sole general partner of Master Fund, Soleus Capital Group, LLC is the sole managing member of Soleus Capital, LLC, SCM is the investment manager for Master Fund, and Soleus GP, LLC is the sole general partner of SCM. Guy Levy is the sole managing member of each of Soleus Capital Group, LLC and of Soleus GP, LLC. Each of Soleus Capital Group, LLC, Soleus Capital, LLC, SCM, Soleus GP, LLC and Mr. Levy disclaims beneficial ownership of these shares held by Master Fund other than for the purpose of determining their obligations under Section 13(d) of the Exchange Act, and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such shares for any other purpose. (2) The percentage set forth in row 11 is calculated based upon 20,163,250 shares of common stock of the Issuer outstanding as of February 26, 2025, as set forth on the cover of the Form 10-K.


SCHEDULE 13G




Comment for Type of Reporting Person:  (1) The shares reported in the table above are held directly by Master Fund. Soleus Capital, LLC is the sole general partner of Master Fund, Soleus Capital Group, LLC is the sole managing member of Soleus Capital, LLC, SCM is the investment manager for Master Fund, and Soleus GP, LLC is the sole general partner of SCM. Guy Levy is the sole managing member of each of Soleus Capital Group, LLC and of Soleus GP, LLC. Each of Soleus Capital Group, LLC, Soleus Capital, LLC, SCM, Soleus GP, LLC and Mr. Levy disclaims beneficial ownership of these shares held by Master Fund other than for the purpose of determining their obligations under Section 13(d) of the Exchange Act, and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such shares for any other purpose. (2) The percentage set forth in row 11 is calculated based upon 20,163,250 shares of common stock of the Issuer outstanding as of February 26, 2025, as set forth on the cover of the Form 10-K.


SCHEDULE 13G




Comment for Type of Reporting Person:  (1) The shares reported in the table above are held directly by Master Fund. Soleus Capital, LLC is the sole general partner of Master Fund, Soleus Capital Group, LLC is the sole managing member of Soleus Capital, LLC, SCM is the investment manager for Master Fund, and Soleus GP, LLC is the sole general partner of SCM. Guy Levy is the sole managing member of each of Soleus Capital Group, LLC and of Soleus GP, LLC. Each of Soleus Capital Group, LLC, Soleus Capital, LLC, SCM, Soleus GP, LLC and Mr. Levy disclaims beneficial ownership of these shares held by Master Fund other than for the purpose of determining their obligations under Section 13(d) of the Exchange Act, and the filing of this report shall not be deemed an admission that any of the foregoing persons is the beneficial owner of such shares for any other purpose. (2) The percentage set forth in row 11 is calculated based upon 20,163,250 shares of common stock of the Issuer outstanding as of February 26, 2025, as set forth on the cover of the Form 10-K.


SCHEDULE 13G



 
Soleus Capital Master Fund, L.P.
 
Signature:Soleus Capital, LLC, its General Partner
Name/Title:Guy Levy/Managing Member
Date:03/19/2025
 
Signature:Soleus Capital Group, LLC, its Managing Manager
Name/Title:Guy Levy/Managing Manager
Date:03/19/2025
 
Soleus Capital, LLC
 
Signature:Soleus Capital Group, LLC, its Managing Manager,
Name/Title:Guy Levy/Managing Manager
Date:03/19/2025
 
Signature:/s/ Guy Levy
Name/Title:Guy Levy/Managing Member
Date:03/19/2025
 
Soleus Capital Group, LLC
 
Signature:/s/ Guy Levy
Name/Title:Guy Levy/Managing Member
Date:03/19/2025
 
Soleus Capital Management, L.P.
 
Signature:Soleus GP, LLC, its General Partner,
Name/Title:Guy Levy/General Partner
Date:03/19/2025
 
Signature:/s/ Guy Levy
Name/Title:Guy Levy/Managing Member
Date:03/19/2025
 
Soleus GP, LLC
 
Signature:/s/ Guy Levy
Name/Title:Guy Levy/Managing Member
Date:03/19/2025
 
Guy Levy
 
Signature:/s/ Guy Levy
Name/Title:Guy Levy
Date:03/19/2025
Exhibit Information

Exhibit A - Joint Filing Agreement

EXHIBIT A

 

JOINT FILING AGREEMENT

 

Soleus Capital Master Fund, L.P., a Cayman Islands exempted limited partnership, Soleus Capital, LLC, a Delaware limited liability company, Soleus Capital Group, LLC, a Delaware limited liability company, Soleus Capital Management, L.P., a Delaware limited partnership, Soleus GP, LLC, a Delaware limited liability company, and Guy Levy, an individual, hereby agree to file jointly the statement on Schedule 13G to which this Joint Filing Agreement is attached, and any amendments thereto which may be deemed necessary, pursuant to Regulation 13D-G under the Securities Exchange Act of 1934, as amended.

 

It is understood and agreed that each of the parties hereto is responsible for the timely filing of such statement and any amendments thereto, and for the completeness and accuracy of the information concerning such party contained therein, but such party is not responsible for the completeness or accuracy of information concerning the other party unless such party knows or has reason to believe that such information is inaccurate.

 

It is understood and agreed that a copy of this Agreement shall be attached as an exhibit to the statement on Schedule 13G, and any amendments hereto, filed on behalf of each of the parties hereto.

 

Date: March 19, 2025 Soleus Capital Master Fund, L.P.
   
  By: Soleus Capital, LLC, its General Partner
   
  By: Soleus Capital Group, LLC, its Managing Manager
   
  By: /s/ Guy Levy
  Name: Guy Levy
  Title: Managing Member
   
Date: March 19, 2025 Soleus Capital, LLC
   
  By: Soleus Capital Group, LLC, its Managing Manager
   
  By: /s/ Guy Levy
  Name: Guy Levy
  Title: Managing Member
   
Date: March 19, 2025 Soleus Capital Group, LLC
   
  By: /s/ Guy Levy
  Name: Guy Levy
  Title: Managing Member
   
Date: March 19, 2025 Soleus Capital Management, L.P.
   
  By: Soleus GP, LLC, its General Partner
   
  By: /s/ Guy Levy
  Name:  Guy Levy
  Title: Managing Member
   
Date: March 19, 2025 Soleus GP, LLC
   
  By: /s/ Guy Levy
  Name: Guy Levy
  Title: Managing Member
   
Date: March 19, 2025 /s/ Guy Levy
  Name: Guy Levy